Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.74 |
| ▸ | APP | P05067 | 3/20 | 0.74 |
| ▸ | TUBB4A | P04350 | 7/20 | 0.68 |
| ▸ | TUBB | P07437 | 7/20 | 0.68 |
| ▸ | TUBA3C | P0DPH7 | 7/20 | 0.68 |
| ▸ | TUBA1B | P68363 | 7/20 | 0.68 |
| ▸ | TUBA4A | P68366 | 7/20 | 0.68 |
| ▸ | TUBB4B | P68371 | 7/20 | 0.68 |
| ▸ | TUBB3 | Q13509 | 7/20 | 0.68 |
| ▸ | TUBB2A | Q13885 | 7/20 | 0.68 |
| ▸ | TUBB8 | Q3ZCM7 | 7/20 | 0.68 |
| ▸ | TUBA3E | Q6PEY2 | 7/20 | 0.68 |
| ▸ | TUBA1A | Q71U36 | 7/20 | 0.68 |
| ▸ | TUBA1C | Q9BQE3 | 7/20 | 0.68 |
| ▸ | TUBB6 | Q9BUF5 | 7/20 | 0.68 |
| ▸ | TUBB2B | Q9BVA1 | 7/20 | 0.68 |
| ▸ | TUBB1 | Q9H4B7 | 7/20 | 0.68 |
| ▸ | MEN1 | O00255 | 5/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.67 |
| ▸ | RAB9A | P51151 | 4/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4623517 | 0.82 | MEN1 (0.72) | MAPTAPPTUBB4ATUBBTUBA3C | |
| SCHEMBL17544358 | 0.82 | APP (1.00) | MAPTAPPTUBB4ATUBBTUBA3C | |
| SCHEMBL30548525 | 0.82 | APP (1.00) | MAPTAPPTUBB4ATUBBTUBA3C | |
| SCHEMBL17544359 | 0.82 | APP (1.00) | MAPTAPPTUBB4ATUBBTUBA3C | |
| SCHEMBL8594710 | 0.82 | MEN1 (0.62) | MAPTAPPTUBB4ATUBBTUBA3C | |
| SCHEMBL8594711 | 0.82 | MEN1 (0.62) | MAPTAPPTUBB4ATUBBTUBA3C | |
| SCHEMBL537904 | 0.80 | NPC1 (1.00) | MAPTTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL29660212 | 0.80 | NPC1 (1.00) | MAPTTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL537905 | 0.80 | NPC1 (1.00) | MAPTTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL6836889 | 0.77 | KDM4E (0.75) | MAPTTUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4746915-A1 | TRIM21-BINDING MOLECULES | United Kingdom Research and Innovation (GB) | 2026-05-27 | — | — | EP | claimed |
| WO-2025021697-A1 | TRIM21-BINDING MOLECULES | UNITED KINGDOM RESEARCH AND INNOVATION (GB) | 2025-01-30 | — | — | WO | claimed |
| EP-4746915-A1 | TRIM21-BINDING MOLECULES | United Kingdom Research and Innovation (GB) | 2026-05-27 | — | — | EP | disclosed |
| WO-2025021697-A1 | TRIM21-BINDING MOLECULES | UNITED KINGDOM RESEARCH AND INNOVATION (GB) | 2025-01-30 | — | — | WO | disclosed |