Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CTSA | P10619 | 8/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CTSD | P07339 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | TDO2 | P48775 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5720914 | 1.00 | POLB (0.55) | POLBHTTNPSR1L3MBTL1SMN1; SMN2 | |
| SCHEMBL12463681 | 1.00 | POLB (0.55) | POLBHTTNPSR1L3MBTL1SMN1; SMN2 | |
| SCHEMBL3385975 | 1.00 | POLB (0.55) | POLBHTTNPSR1L3MBTL1SMN1; SMN2 | |
| SCHEMBL13917991 | 0.87 | POLB (0.47) | POLBHTTNPSR1L3MBTL1SMN1; SMN2 | |
| SCHEMBL12463288 | 0.87 | POLB (0.47) | POLBHTTNPSR1L3MBTL1SMN1; SMN2 | |
| SCHEMBL14408244 | 0.87 | CYP2D6 (0.48) | POLBHTTNPSR1L3MBTL1SMN1; SMN2 | |
| SCHEMBL12463711 | 0.87 | POLB (0.47) | POLBHTTNPSR1L3MBTL1SMN1; SMN2 | |
| SCHEMBL381854 | 0.85 | HTT (0.50) | POLBHTTNPSR1L3MBTL1SMN1; SMN2 | |
| SCHEMBL27599721 | 0.84 | L3MBTL1 (0.40) | POLBHTTNPSR1L3MBTL1SMN1; SMN2 | |
| SCHEMBL20546453 | 0.84 | CTSA (0.59) | CTSA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4746915-A1 | TRIM21-BINDING MOLECULES | United Kingdom Research and Innovation (GB) | 2026-05-27 | — | — | EP | disclosed |
| WO-2025021697-A1 | TRIM21-BINDING MOLECULES | UNITED KINGDOM RESEARCH AND INNOVATION (GB) | 2025-01-30 | — | — | WO | disclosed |