SCHEMBL31364579

SCHEMBL31364579

Fc1ccc(-n2nc(C(F)(F)F)cc2CCl)cc1F

nearest known ligand 0.46

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 19/20 0.46
PTGS1 P23219 1/20 0.44
PTGS2 P35354 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13172610 0.85 TRPV1 (0.46) TRPV1PTGS1PTGS2
SCHEMBL31364578 0.85 TRPV1 (0.48) TRPV1PTGS2
SCHEMBL31364584 0.85 PTGS2 (0.61) TRPV1PTGS1PTGS2
SCHEMBL13194430 0.85 TRPV1 (0.51) TRPV1
Hydrochloric Acid SCHEMBL12982348 0.84 TRPV1 (0.45) TRPV1PTGS1PTGS2
SCHEMBL31364583 0.77 TRPV1 (0.44) TRPV1
SCHEMBL31364587 0.77 TRPV1 (0.44) TRPV1
SCHEMBL287490 0.76 TRPV1 (0.51) TRPV1PTGS1PTGS2
SCHEMBL27955897 0.73 KCNJ6 (0.50) TRPV1PTGS1PTGS2
SCHEMBL31504003 0.73 STIM1 (0.48) TRPV1PTGS1PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025021650-A1 HERBICIDAL PYRAZOLE COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2025-01-30 WO disclosed