Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | SCN1A | P35498 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | LIG1 | P18858 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL306669 | 1.00 | SMYD3 (0.57) | SMYD3GAAKMT2AMEN1CREBBP | |
| SCHEMBL17476309 | 0.86 | SMYD3 (0.56) | SMYD3GAAKMT2ACREBBPBRD4 | |
| SCHEMBL7279844 | 0.86 | SMYD3 (0.60) | SMYD3GAAKMT2ACREBBPBRD4 | |
| Hydrochloric Acid SCHEMBL7373686 | 0.84 | SMYD3 (0.58) | SMYD3GAAKMT2ACREBBPBRD4 | |
| SCHEMBL29753562 | 0.82 | SMYD3 (0.56) | SMYD3GAAKMT2ACREBBPBRD4 | |
| SCHEMBL17476304 | 0.82 | SMYD3 (0.56) | SMYD3GAAKMT2ACREBBPBRD4 | |
| SCHEMBL1340605 | 0.82 | SMYD3 (0.56) | SMYD3GAAKMT2ACREBBPBRD4 | |
| SCHEMBL6181892 | 0.79 | SMYD3 (0.50) | SMYD3GAACREBBPBRD4PARP1 | |
| SCHEMBL4317646 | 0.78 | SMYD3 (0.51) | SMYD3GAACREBBPBRD4HTR1A | |
| SCHEMBL10222933 | 0.78 | SMYD3 (0.49) | SMYD3GAAKMT2ACREBBPBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025020886-A1 | AZAQUINAZOLINE RING DERIVATIVE AND USE THEREOF | 浙江星浩澎博医药有限公司 | 2025-01-30 | — | — | WO | disclosed |