Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.46 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.46 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MET | P08581 | 1/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | IDH1 | O75874 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31364870 | 0.82 | TP53 (0.43) | KMT2AMEN1TP53MAPTHPGD | |
| SCHEMBL31364959 | 0.81 | TP53 (0.45) | KMT2AMEN1TP53MAPTHPGD | |
| SCHEMBL31365037 | 0.81 | TP53 (0.45) | KMT2AMEN1TP53MAPTHPGD | |
| SCHEMBL31364909 | 0.81 | MEN1 (0.41) | KMT2AMEN1TP53MAPTHPGD | |
| SCHEMBL31365025 | 0.79 | TP53 (0.43) | KMT2AMEN1TP53MAPTHPGD | |
| SCHEMBL31364949 | 0.78 | LMNA (0.45) | KMT2AMEN1TP53MAPTHPGD | |
| SCHEMBL31364893 | 0.78 | TP53 (0.42) | KMT2AMEN1TP53MAPTHPGD | |
| SCHEMBL31364831 | 0.76 | TP53 (0.40) | KMT2AMEN1TP53MAPTHPGD | |
| SCHEMBL31365057 | 0.76 | LMNA (0.45) | KMT2AMEN1TP53MAPTHPGD | |
| SCHEMBL15063651 | 0.75 | S1PR3 (0.42) | KMT2AMEN1TP53MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025056065-A1 | CHEMOKINE RECEPTOR ANTAGONIST, PHARMACEUTICAL COMPOSITION, AND USE | 上海医药集团股份有限公司 | 2025-03-20 | — | — | WO | disclosed |
| CN-119638669-A | Chemokine receptor antagonist, pharmaceutical composition and application | 上海医药集团股份有限公司 | 2025-03-18 | — | — | CN | disclosed |