Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CCR4 | P51679 | 15/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31365023 | 0.91 | LMNA (0.33) | LMNATP53HTT | |
| SCHEMBL31364833 | 0.90 | LMNA (0.37) | LMNATP53HTTCCR4P2RX7 | |
| SCHEMBL31364789 | 0.89 | TP53 (0.36) | LMNATP53HTTCCR4P2RX7 | |
| SCHEMBL31364973 | 0.89 | LMNA (0.36) | LMNATP53HTTCCR4P2RX7 | |
| SCHEMBL31531580 | 0.89 | LMNA (0.36) | LMNATP53HTTCCR4P2RX7 | |
| SCHEMBL31531563 | 0.88 | LMNA (0.35) | LMNATP53HTTCCR4P2RX7 | |
| SCHEMBL31364895 | 0.88 | LMNA (0.35) | LMNATP53HTTCCR4PDE2A | |
| SCHEMBL31364817 | 0.88 | GLP1R (0.36) | LMNATP53HTTCCR4PDE2A | |
| SCHEMBL31364967 | 0.88 | LMNA (0.35) | LMNATP53HTTCCR4P2RX7 | |
| SCHEMBL31364938 | 0.87 | CCR4 (0.35) | LMNATP53HTTCCR4P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025056065-A1 | CHEMOKINE RECEPTOR ANTAGONIST, PHARMACEUTICAL COMPOSITION, AND USE | 上海医药集团股份有限公司 | 2025-03-20 | — | — | WO | disclosed |
| CN-119638669-A | Chemokine receptor antagonist, pharmaceutical composition and application | 上海医药集团股份有限公司 | 2025-03-18 | — | — | CN | disclosed |