Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | SCN1A | P35498 | 4/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 4/20 | 0.36 |
| ▸ | SCN8A | Q9UQD0 | 4/20 | 0.36 |
| ▸ | IDH1 | O75874 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31365057 | 0.88 | LMNA (0.45) | LMNAHTTTP53MEN1KMT2A | |
| SCHEMBL31364997 | 0.86 | LMNA (0.43) | LMNAHTTTP53MEN1KMT2A | |
| SCHEMBL31364959 | 0.80 | TP53 (0.45) | LMNAHTTTP53MEN1KMT2A | |
| SCHEMBL31364955 | 0.80 | TSHR (0.40) | LMNAHTTTP53MEN1KMT2A | |
| SCHEMBL31364893 | 0.80 | TP53 (0.42) | LMNAHTTTP53MEN1KMT2A | |
| SCHEMBL31364956 | 0.77 | LMNA (0.42) | LMNAHTTTP53MEN1KMT2A | |
| SCHEMBL14995049 | 0.75 | MEN1 (0.38) | LMNAHTTTP53MEN1KMT2A | |
| SCHEMBL14995048 | 0.75 | MEN1 (0.38) | LMNAHTTTP53MEN1KMT2A | |
| SCHEMBL31365037 | 0.75 | TP53 (0.45) | LMNAHTTTP53MEN1KMT2A | |
| SCHEMBL3127450 | 0.74 | EGFR (0.40) | SCN1ASCN5ASCN8A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025056065-A1 | CHEMOKINE RECEPTOR ANTAGONIST, PHARMACEUTICAL COMPOSITION, AND USE | 上海医药集团股份有限公司 | 2025-03-20 | — | — | WO | disclosed |
| CN-119638669-A | Chemokine receptor antagonist, pharmaceutical composition and application | 上海医药集团股份有限公司 | 2025-03-18 | — | — | CN | disclosed |