Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.34 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.34 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.34 |
| ▸ | TNF | P01375 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31365016 | 0.92 | TSHR (0.37) | TSHRALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL31364929 | 0.91 | TNF (0.37) | TSHRALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL31365011 | 0.90 | MEN1 (0.36) | TSHRALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL31364824 | 0.88 | MAPT (0.37) | TSHRALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL31365033 | 0.84 | TNF (0.36) | TSHRALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL15053385 | 0.83 | TSHR (0.47) | TSHRALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL31531593 | 0.83 | TSHR (0.47) | TSHRALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL15053383 | 0.83 | TSHR (0.47) | TSHRALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL31364909 | 0.80 | MEN1 (0.41) | TSHRMEN1KMT2ALMNATP53 | |
| SCHEMBL31364954 | 0.80 | MEN1 (0.39) | TSHRALDH1A1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025056065-A1 | CHEMOKINE RECEPTOR ANTAGONIST, PHARMACEUTICAL COMPOSITION, AND USE | 上海医药集团股份有限公司 | 2025-03-20 | — | — | WO | disclosed |
| CN-119638669-A | Chemokine receptor antagonist, pharmaceutical composition and application | 上海医药集团股份有限公司 | 2025-03-18 | — | — | CN | disclosed |