Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TNF | P01375 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.31 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.31 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.31 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | EEF2K | O00418 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31365033 | 0.92 | TNF (0.36) | TSHRALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL31365010 | 0.92 | TSHR (0.40) | TSHRALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL31364929 | 0.85 | TNF (0.37) | TSHRALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL31365011 | 0.82 | MEN1 (0.36) | TSHRALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL31364824 | 0.80 | MAPT (0.37) | TSHRALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL31365031 | 0.80 | LMNA (0.39) | TSHRMEN1KMT2AHTTMAPT | |
| SCHEMBL15053385 | 0.75 | TSHR (0.47) | TSHRALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL31365013 | 0.75 | LMNA (0.37) | MEN1KMT2AHTTMAPTLMNA | |
| SCHEMBL31531593 | 0.75 | TSHR (0.47) | TSHRALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL15053383 | 0.75 | TSHR (0.47) | TSHRALDH1A1MAPK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025056065-A1 | CHEMOKINE RECEPTOR ANTAGONIST, PHARMACEUTICAL COMPOSITION, AND USE | 上海医药集团股份有限公司 | 2025-03-20 | — | — | WO | disclosed |