Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.48 |
| ▸ | PDE2A | O00408 | 2/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.36 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.36 |
| ▸ | TRPV3 | Q8NET8 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | PI4KA | P42356 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL998305 | 1.00 | TRPV4 (0.48) | TRPV4PDE2AADRB2P2RX3P2RX7 | |
| SCHEMBL367869 | 1.00 | TRPV4 (0.48) | TRPV4PDE2AADRB2P2RX3P2RX7 | |
| SCHEMBL347477 | 1.00 | TRPV4 (0.48) | TRPV4PDE2AADRB2P2RX3P2RX7 | |
| Hydrochloric Acid SCHEMBL4525613 | 0.98 | TRPV4 (0.47) | TRPV4PDE2AADRB2P2RX3P2RX7 | |
| Hydrochloric Acid SCHEMBL29220549 | 0.98 | TRPV4 (0.47) | TRPV4PDE2AADRB2P2RX3P2RX7 | |
| Hydrochloric Acid SCHEMBL28929954 | 0.98 | TRPV4 (0.47) | TRPV4PDE2AADRB2P2RX3P2RX7 | |
| Hydrochloric Acid SCHEMBL14480234 | 0.98 | TRPV4 (0.47) | TRPV4PDE2AADRB2P2RX3P2RX7 | |
| Hydrochloric Acid SCHEMBL28673757 | 0.98 | TRPV4 (0.47) | TRPV4PDE2AADRB2P2RX3P2RX7 | |
| Hydrochloric Acid SCHEMBL1000893 | 0.98 | TRPV4 (0.47) | TRPV4PDE2AADRB2P2RX3P2RX7 | |
| Hydrochloric Acid SCHEMBL29220551 | 0.98 | TRPV4 (0.47) | TRPV4PDE2AADRB2P2RX3P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113226462-B | Heteroaromatic compounds as VANIN inhibitors | 勃林格殷格翰国际公司 | 2025-02-11 | — | — | CN | disclosed |