Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.71 |
| ▸ | GAA | P10253 | 4/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.71 |
| ▸ | HPGD | P15428 | 3/20 | 0.71 |
| ▸ | GLA | P06280 | 3/20 | 0.71 |
| ▸ | MAPT | P10636 | 3/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.71 |
| ▸ | NQO2 | P16083 | 6/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.56 |
| ▸ | TNKS2 | Q9H2K2 | 4/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26607754 | 1.00 | KDM4E (0.71) | KDM4EGAAALDH1A1HPGDGLA | |
| SCHEMBL9516719 | 0.83 | KDM4E (0.51) | KDM4EGAAALDH1A1HPGDGLA | |
| SCHEMBL4814287 | 0.83 | MAPT (1.00) | KDM4EGAAALDH1A1HPGDGLA | |
| SCHEMBL11140695 | 0.83 | KDM4E (1.00) | KDM4EGAAALDH1A1HPGDGLA | |
| SCHEMBL13480899 | 0.79 | AR (0.50) | KDM4EGAAALDH1A1HPGDGLA | |
| SCHEMBL19667052 | 0.76 | NQO2 (0.67) | KDM4EGAAALDH1A1HPGDGLA | |
| SCHEMBL4043163 | 0.76 | KDM4E (0.56) | KDM4EGAAALDH1A1HPGDGLA | |
| SCHEMBL16510570 | 0.74 | KDM4E (0.61) | KDM4EGAAALDH1A1HPGDGLA | |
| SCHEMBL26607762 | 0.73 | KDM4E (0.67) | KDM4EGAAALDH1A1HPGDGLA | |
| SCHEMBL17509835 | 0.73 | KDM4E (0.53) | KDM4EGAAALDH1A1HPGDGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250382308-A1 | COMPOUNDS ACTIVE TOWARDS BROMODOMAINS | NUEVOLUTION AS (US) | 2025-12-18 | — | — | US | disclosed |
| CN-119365455-A | Having a bromodomain active compounds | 纽韦卢森公司 | 2025-01-24 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250382308-A1 | COMPOUNDS ACTIVE TOWARDS BROMODOMAINS | BRD4, BRD3, EP300 | KDM4E 438/4885GAA 1706/4885ALDH1A1 2907/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.