Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 1.00 |
| ▸ | GAA | P10253 | 4/20 | 1.00 |
| ▸ | GLA | P06280 | 3/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 1.00 |
| ▸ | HPGD | P15428 | 3/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 1.00 |
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | NQO2 | P16083 | 6/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TNKS2 | Q9H2K2 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31365385 | 0.83 | KDM4E (0.71) | KDM4EGAAGLAALDH1A1HPGD | |
| SCHEMBL26607754 | 0.83 | KDM4E (0.71) | KDM4EGAAGLAALDH1A1HPGD | |
| SCHEMBL26607762 | 0.80 | KDM4E (0.67) | KDM4EGAAGLAALDH1A1HPGD | |
| SCHEMBL4814287 | 0.79 | MAPT (1.00) | KDM4EGAAGLAALDH1A1HPGD | |
| SCHEMBL8066122 | 0.79 | KDM4E (0.65) | KDM4EGAAGLAALDH1A1HPGD | |
| SCHEMBL14892531 | 0.73 | KDM4E (0.57) | KDM4EGAAGLAALDH1A1HPGD | |
| SCHEMBL19667052 | 0.72 | NQO2 (0.67) | KDM4EGAAGLAALDH1A1HPGD | |
| SCHEMBL14726207 | 0.72 | KDM4E (0.56) | KDM4EGAAGLAALDH1A1HPGD | |
| SCHEMBL4043163 | 0.71 | KDM4E (0.56) | KDM4EGAAGLAALDH1A1HPGD | |
| SCHEMBL8030947 | 0.71 | ALDH1A1 (0.55) | KDM4EGAAGLAALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4400507-A | FOR COLORING POLYMERS, LACQUERS | CIBA-GEIGY CORPORATION (US) | 1983-08-23 | — | — | US | disclosed |
| US-4263205-A | FOR COLORING POLYMERS, LACQUERS | CIBA-GEIGY CORPORATION (US) | 1981-04-21 | — | — | US | disclosed |
| US-4262120-A | YELLOW TO ORANGE SHADES OF GOOD FASTNESS | CIBA-GEIGY CORPORATION (US) | 1981-04-14 | — | — | US | disclosed |