Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 4/20 | 0.60 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.50 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.47 |
| ▸ | CCKAR | P32238 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | BRD2 | P25440 | 1/20 | 0.42 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | NOTCH1 | P46531 | 1/20 | 0.42 |
| ▸ | RBPJ | Q06330 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26333834 | 1.00 | CCKBR (0.60) | CCKBRHDAC3HDAC1HDAC6HDAC8 | |
| SCHEMBL25412491 | 0.93 | CCKBR (0.59) | CCKBRHDAC3HDAC1HDAC6HDAC8 | |
| SCHEMBL31366583 | 0.93 | CCKBR (0.59) | CCKBRHDAC3HDAC1HDAC6HDAC8 | |
| SCHEMBL25412494 | 0.93 | CCKBR (0.59) | CCKBRHDAC3HDAC1HDAC6HDAC8 | |
| SCHEMBL25412495 | 0.93 | CCKBR (0.59) | CCKBRHDAC3HDAC1HDAC6HDAC8 | |
| SCHEMBL31366624 | 0.92 | CCKBR (0.59) | CCKBRHDAC3HDAC1HDAC6HDAC8 | |
| SCHEMBL31630024 | 0.92 | CCKBR (0.59) | CCKBRHDAC3HDAC1HDAC6HDAC8 | |
| SCHEMBL25410334 | 0.89 | HDAC3 (0.58) | CCKBRHDAC3HDAC1HDAC6HDAC8 | |
| SCHEMBL31366620 | 0.89 | HDAC3 (0.58) | CCKBRHDAC3HDAC1HDAC6HDAC8 | |
| SCHEMBL25410339 | 0.89 | HDAC3 (0.58) | CCKBRHDAC3HDAC1HDAC6HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250197360-A1 | NOVEL DIAZEPINES THAT TARGET YELLOW FEVER VIRUS NON-STRUCTURAL 4B (NS4B) PROTEIN AND THEIR METHOD OF USE | BARUCH S. BLUMBERG INSTITUTE | 2025-06-19 | — | — | US | disclosed |
| CN-119072467-A | Novel diazapine compounds targeting yellow fever virus non-structural 4B (NS 4B) protein and methods of use thereof | 巴鲁克斯布伦博格研究所 | 2024-12-03 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250197360-A1 | NOVEL DIAZEPINES THAT TARGET YELLOW FEVER VIRUS NON-STRUCTURAL 4B (NS4B) PROTEIN AND THEIR METHOD OF USE | CUL4B, BRD4, CUL4A | CCKBR 3175/4885HDAC3 1588/4885HDAC1 2365/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.