Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Dimethylaminoethanol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethylaminoethanol SCHEMBL1007646 | 0.96 | MAPT (0.86) | — | |
| Dimethylaminoethanol SCHEMBL15916955 | 0.96 | — | — | |
| Dimethylaminoethanol SCHEMBL5945 | 0.96 | — | — | |
| Dimethylaminoethanol SCHEMBL16756236 | 0.96 | — | — | |
| Dimethylaminoethanol SCHEMBL2149038 | 0.96 | MAPT (1.00) | — | |
| Dimethylaminoethanol SCHEMBL13169672 | 0.96 | — | — | |
| Dimethylaminoethanol SCHEMBL25210984 | 0.92 | — | — | |
| Dimethylaminoethanol SCHEMBL6885300 | 0.92 | — | — | |
| Dimethylaminoethanol SCHEMBL5471917 | 0.92 | — | — | |
| Dimethylaminoethanol SCHEMBL67457 | 0.92 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1217 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118271422-A | Transfection complexes and methods of use thereof | 分子传递有限公司 | 2024-07-02 | — | — | CN | claimed |
| CN-118251497-A | Lipid compositions comprising peptide-lipid conjugates | 阿克丘勒斯治疗公司 | 2024-06-25 | — | — | CN | claimed |
| CN-118201605-A | POEGMA-based lipid nanoparticles | 杜克大学 | 2024-06-14 | — | — | CN | claimed |
| CN-111867634-B | Enhancement of translocation of micro/nanoparticles across mucus layers using alginate oligomers | 阿尔吉法玛公司 | 2024-06-11 | — | — | CN | claimed |
| CN-118043068-A | RNA vaccine | 阿克丘勒斯治疗公司 | 2024-05-14 | — | — | CN | claimed |
| CN-117615753-A | Lipid nanoparticle and method for preparing the same | 泰纳治疗公司 | 2024-02-27 | — | — | CN | claimed |
| CN-117396193-A | Compositions and methods for delivering RNA | 再生技术有限责任公司 | 2024-01-12 | — | — | CN | claimed |
| US-11717481-B2 | Reduction of flake-like aggregation in nanoparticulate active agent compositions | ALKERMES PHARMA IRELAND LIMITED (IE) | 2023-08-08 | — | — | US | claimed |
| WO-2023076902-A1 | POEGMA-BASED LIPID NANOPARTICLES | DUKE UNIVERSITY (US) | 2023-05-04 | — | — | WO | claimed |
| US-20220211626-A1 | REDUCTION OF FLAKE-LIKE AGGREGATION IN NANOPARTICULATE ACTIVE AGENT COMPOSITIONS | JPMORGAN CHASE BANK, N.A. AS ADMINISTRATIVE AGENT | 2022-07-07 | — | — | US | claimed |
| US-20030181411-A1 | Contacting and adsorbing an insoluble enzyme inhibitor with a surface stabilizer | ELAN PHARMA INTERNATIONAL LTD. | 2003-09-25 | — | — | US | claimed |
| WO-2003066021-A2 | DRUG NANOPARTICLES WITH LYSOZYME SURFACE STABILISER | ELAN PHARMA INTERNATIONAL, LTD. (IE) | 2003-08-14 | — | — | WO | claimed |
| US-20030137067-A1 | Compositions having a combination of immediate release and controlled release characteristics | ELAN PHARMA INTERNATIONAL LTD. | 2003-07-24 | — | — | US | claimed |
| US-20030095928-A1 | Nanoparticulate insulin | ELAN PHARMA INTERNATIONAL LIMITED | 2003-05-22 | — | — | US | claimed |
| WO-2003030872-A2 | COMPOSITIONS HAVING A COMBINATION OF PARTICLES FOR IMMEDIATE RELEASE AND FOR CONTROLLED RELEASE | ELAN PHARMA INTERNATIONAL LTD. (IE) | 2003-04-17 | — | — | WO | claimed |
| WO-2003024425-A1 | NANOPARTICULATE INSULIN FORMULATIONS | ELAN PHARMA INTERNATIONAL, LTD. (IE) | 2003-03-27 | — | — | WO | claimed |
| WO-2001078785-A2 | ACTIVE SUBSTANCE CONJUGATES WITH INTRACELLULARLY ACTIVE LIGANDS | BIOTECTID GMBH (DE) | 2001-10-25 | — | — | WO | claimed |
| WO-2001051767-A2 | ADDITION OF SOLIDS TO GENERATE VISCOSITY DOWNHOLE | SCHLUMBERGER TECHNOLOGY CORPORATION (US) | 2001-07-19 | — | — | WO | claimed |
| EP-1109926-A1 | CONDENSED PLASMID-LIPOSOME COMPLEX FOR TRANSFECTION | ALZA CORPORATION (US) | 2001-06-27 | — | — | EP | claimed |
| WO-2000015825-A1 | CONDENSED PLASMID-LIPOSOME COMPLEX FOR TRANSFECTION | ALZA CORPORATION (US) | 2000-03-23 | — | — | WO | claimed |