Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 8/20 | 0.77 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.53 |
| ▸ | FNTA | P49354 | 5/20 | 0.39 |
| ▸ | FNTB | P49356 | 5/20 | 0.39 |
| ▸ | PGGT1B | P53609 | 5/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.33 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.32 |
| ▸ | ATXN2 | Q99700 | 1/20 | 0.32 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.32 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.32 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1041433 | 0.90 | CYP11B2 (0.79) | CYP11B2CYP19A1FNTAFNTBPGGT1B | |
| SCHEMBL30385317 | 0.87 | CYP11B2 (1.00) | CYP11B2CYP19A1FNTAFNTBPGGT1B | |
| SCHEMBL1041019 | 0.87 | CYP11B2 (1.00) | CYP11B2CYP19A1FNTAFNTBPGGT1B | |
| SCHEMBL30385322 | 0.85 | CYP11B2 (0.81) | CYP11B2CYP19A1FNTAFNTBPGGT1B | |
| SCHEMBL1038849 | 0.85 | CYP11B2 (0.81) | CYP11B2CYP19A1FNTAFNTBPGGT1B | |
| SCHEMBL1077701 | 0.76 | CYP11B2 (0.73) | CYP11B2CYP19A1 | |
| SCHEMBL1040020 | 0.76 | CYP11B2 (1.00) | CYP11B2CYP19A1CYP11B1 | |
| SCHEMBL23047216 | 0.76 | CYP11B2 (0.81) | CYP11B2CYP19A1CYP11B1 | |
| SCHEMBL16200646 | 0.76 | CYP11B2 (0.80) | CYP11B2CYP19A1CYP11B1 | |
| SCHEMBL1040490 | 0.75 | CYP11B2 (1.00) | CYP11B2CYP19A1CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113166204-B | Cyclic peptides as inhibitors of proprotein convertase subtilisin/kexin type 9 (PCSK 9) for the treatment of metabolic disorders | 诺华股份有限公司 | 2025-01-28 | — | — | CN | disclosed |