Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 3/20 | 0.39 |
| ▸ | NOS1 | P29475 | 2/20 | 0.37 |
| ▸ | NOS2 | P35228 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14736413 | 0.83 | PIK3CD (0.44) | PIK3CDSMN1; SMN2MAPK1ALDH1A1L3MBTL1 | |
| SCHEMBL14736911 | 0.82 | MAPT (0.46) | PIK3CDLMNAPDE4BHTTMAPT | |
| SCHEMBL19157185 | 0.82 | PIK3CD (0.43) | PIK3CDNOS1NOS2SMN1; SMN2PDE4B | |
| SCHEMBL14736001 | 0.74 | PIK3CD (0.44) | PIK3CDSMN1; SMN2PDE4BALDH1A1L3MBTL1 | |
| SCHEMBL14736691 | 0.74 | PIK3CD (0.42) | PIK3CD | |
| SCHEMBL14735938 | 0.72 | PIK3CD (0.41) | PIK3CDPDE4BHTTMAPTMAPK1 | |
| SCHEMBL21174644 | 0.71 | PIK3CD (0.39) | PIK3CD | |
| SCHEMBL14735979 | 0.67 | GLRA1 (0.41) | PIK3CDSMN1; SMN2POLBCHRM1PDE4B | |
| SCHEMBL14736290 | 0.66 | PIK3CD (0.42) | PIK3CD | |
| SCHEMBL31150613 | 0.66 | ALDH1A1 (0.49) | LMNASMN1; SMN2POLBCHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3888657-B1 | HETEROCYCLYLAMINES AS PI3K INHIBITORS | INCYTE HOLDINGS CORP (US) | 2025-03-19 | — | — | EP | disclosed |