Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20846774 | 0.79 | TNKS (0.36) | GAA | |
| SCHEMBL1439201 | 0.70 | USP2 (0.33) | — | |
| SCHEMBL2518191 | 0.67 | — | — | |
| SCHEMBL1906501 | 0.67 | — | — | |
| SCHEMBL78201 | 0.67 | — | — | |
| SCHEMBL14631330 | 0.67 | — | — | |
| SCHEMBL12417593 | 0.66 | SLC6A2 (0.36) | — | |
| SCHEMBL13424726 | 0.66 | TNKS (0.34) | GAA | |
| SCHEMBL31019861 | 0.65 | TACR1 (0.32) | — | |
| Flumetramide SCHEMBL9576017 | 0.65 | PRKAB2 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4739685-A1 | 1,6-NAPHTHRIDINE COMPOUNDS AS SMARCA2 INHIBITORS USEFUL FOR THE TREATMENT OF SMARCA4 DEFICIENT CANCERS | Janssen Pharmaceutica NV (BE) | 2026-05-13 | — | — | EP | disclosed |
| WO-2025008061-A1 | 1,6-NAPHTHRIDINE COMPOUNDS AS SMARCA2 INHIBITORS USEFUL FOR THE TREATMENT OF SMARCA4 DEFICIENT CANCERS | JANSSEN PHARMACEUTICA NV (BE) | 2025-01-09 | — | — | WO | disclosed |