Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26744923 | 0.78 | PER2 (0.41) | BRD4 | |
| SCHEMBL26744978 | 0.78 | PER2 (0.41) | BRD4 | |
| SCHEMBL3429403 | 0.70 | KMT2A (0.32) | BRD4 | |
| SCHEMBL9559747 | 0.68 | TAAR1 (0.37) | — | |
| SCHEMBL1712652 | 0.67 | PDK2 (0.39) | BRD4 | |
| SCHEMBL1712650 | 0.66 | PDK2 (0.39) | BRD4 | |
| SCHEMBL14270966 | 0.66 | POLB (0.37) | BRD4 | |
| SCHEMBL10543893 | 0.66 | KMT2A (0.35) | — | |
| SCHEMBL4338414 | 0.64 | CHRM2 (0.47) | BRD4 | |
| SCHEMBL14839577 | 0.64 | PTGER4 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4739685-A1 | 1,6-NAPHTHRIDINE COMPOUNDS AS SMARCA2 INHIBITORS USEFUL FOR THE TREATMENT OF SMARCA4 DEFICIENT CANCERS | Janssen Pharmaceutica NV (BE) | 2026-05-13 | — | — | EP | disclosed |
| WO-2025008061-A1 | 1,6-NAPHTHRIDINE COMPOUNDS AS SMARCA2 INHIBITORS USEFUL FOR THE TREATMENT OF SMARCA4 DEFICIENT CANCERS | JANSSEN PHARMACEUTICA NV (BE) | 2025-01-09 | — | — | WO | disclosed |