Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | APLNR | P35414 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 2/20 | 0.36 |
| ▸ | CTSK | P43235 | 2/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
| ▸ | HMGCR | P04035 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8284352 | 0.83 | MEN1 (0.45) | MEN1GAAKMT2ATDP1MAOA | |
| SCHEMBL28139028 | 0.83 | MEN1 (0.41) | MEN1GAAKMT2ATDP1MAOA | |
| SCHEMBL3049060 | 0.81 | MEN1 (0.50) | MEN1GAAKMT2ATDP1MAOA | |
| SCHEMBL13449471 | 0.81 | TDP1 (0.49) | MEN1GAAKMT2ATDP1MAOA | |
| SCHEMBL14744344 | 0.81 | TDP1 (0.44) | MEN1GAAKMT2ATDP1MAOA | |
| SCHEMBL17941927 | 0.80 | MEN1 (0.42) | MEN1GAAKMT2ATDP1CA1 | |
| SCHEMBL1536313 | 0.80 | HMGCR (0.50) | MEN1GAAKMT2ATDP1MAOA | |
| SCHEMBL22950318 | 0.80 | TDP1 (0.43) | MEN1GAAKMT2ATDP1MAOA | |
| SCHEMBL2374951 | 0.80 | HMGCR (0.50) | MEN1GAAKMT2ATDP1MAOA | |
| SCHEMBL1233767 | 0.80 | TDP1 (0.43) | MEN1GAAKMT2ATDP1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119451950-A | Compounds and methods for degrading casein kinase 1 alpha | 匹恩治疗株式会社 | 2025-02-14 | — | — | CN | disclosed |