Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 3/20 | 0.37 |
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | CA9 | Q16790 | 3/20 | 0.37 |
| ▸ | APLNR | P35414 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 2/20 | 0.34 |
| ▸ | CTSK | P43235 | 2/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31368614 | 0.83 | MEN1 (0.47) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL3049060 | 0.79 | MEN1 (0.50) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL1536313 | 0.77 | HMGCR (0.50) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL2374951 | 0.77 | HMGCR (0.50) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL12698678 | 0.76 | TDP1 (0.48) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL4202727 | 0.76 | TDP1 (0.48) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL843323 | 0.76 | TDP1 (0.48) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL5548918 | 0.76 | MEN1 (0.47) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL28460437 | 0.75 | MEN1 (0.46) | MEN1KMT2AGAATDP1MAOA | |
| SCHEMBL17141089 | 0.75 | MEN1 (0.46) | MEN1KMT2AGAATDP1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005082362-A1 | THERAPEUTIC COMBINATIONS | PFIZER INC. (US) | 2005-09-09 | — | — | WO | disclosed |