SCHEMBL31368632

SCHEMBL31368632

COC(=O)c1c(C)ncnc1Cl

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA7 P43166 1/20 0.38
CA9 Q16790 1/20 0.38
CA14 Q9ULX7 1/20 0.38
KDM4E B2RXH2 3/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
CYP3A4 P08684 2/20 0.37
ACHE P22303 1/20 0.37
PLA2G2A P14555 1/20 0.37
TSHR P16473 3/20 0.36
ALDH1A1 P00352 3/20 0.36
HPGD P15428 3/20 0.36
HSD17B10 Q99714 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
HTT P42858 2/20 0.36
GLA P06280 1/20 0.36
NPC1 O15118 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15155242 1.00 CA12 (0.38) CA12CA1CA2CA7CA9
SCHEMBL2185738 0.88 CA12 (0.43) CA12CA1CA2CA7CA9
SCHEMBL3321442 0.86 CA12 (0.45) CA12CA1CA2CA7CA9
SCHEMBL3110696 0.82 PDE4D (0.46) CA12CA1CA2CA7CA9
SCHEMBL18923135 0.80 EGFR (0.44) CA12CA1CA2CA7CA9
SCHEMBL30981526 0.80 ALDH1A1 (0.31) ALDH1A1
SCHEMBL20061357 0.79 KMT2A (0.36) KDM4EMEN1KMT2ACYP3A4TSHR
SCHEMBL16984947 0.79 ALDH1A1 (0.46) KDM4EMEN1KMT2ATSHRALDH1A1
SCHEMBL12233077 0.79 ALDH1A1 (0.35) ALDH1A1SMN1; SMN2POLB
SCHEMBL16712807 0.78 ALDH1A1 (0.44) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024250984-A1 ANTIBODY-DRUG CONJUGATE, AND PHARMACEUTICAL COMPOSITION THEREOF, PREPARATION THEREFOR AND USE THEREOF 上海维申医药有限公司 2024-12-12 WO disclosed