Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GOT1 | P17174 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 2/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.32 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31371610 | 0.84 | IL1B (0.35) | DYRK1AALDH1A1ESR1HSD17B10 | |
| SCHEMBL31371639 | 0.81 | SCN9A (0.36) | DYRK1ARAB9AESR1KMT2A | |
| SCHEMBL28433440 | 0.78 | ADORA1 (0.44) | DYRK1AMAPTSMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL31371634 | 0.76 | ESR2 (0.42) | L3MBTL1MAPTSMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL31371516 | 0.72 | PDE5A (0.39) | HTT | |
| SCHEMBL2201586 | 0.72 | DYRK1A (0.47) | DYRK1AMAPTSMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL30413717 | 0.72 | DYRK1A (0.47) | DYRK1AMAPTSMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL580923 | 0.68 | ADORA1 (0.41) | MAPTSMN1; SMN2ALDH1A1HPGDKMT2A | |
| SCHEMBL31371717 | 0.68 | SCN9A (0.42) | MAPTALDH1A1KDM4E | |
| SCHEMBL31371910 | 0.66 | SCN9A (0.41) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025034849-A1 | FUSED PYRIDAZINES FOR THE TREATMENT OF CANCER AND OTHER INDICATIONS | THERAS, INC. (US) | 2025-02-13 | — | — | WO | disclosed |