Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 17/20 | 0.53 |
| ▸ | CCND3 | P30281 | 10/20 | 0.53 |
| ▸ | CCND1 | P24385 | 8/20 | 0.53 |
| ▸ | CDK2 | P24941 | 2/20 | 0.53 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.53 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.53 |
| ▸ | CDK1 | P06493 | 3/20 | 0.43 |
| ▸ | CDK9 | P50750 | 2/20 | 0.43 |
| ▸ | AURKA | O14965 | 2/20 | 0.42 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.42 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20425411 | 1.00 | CDK4 (0.53) | CDK4CCND3CCND1CDK2CCNE1 | |
| SCHEMBL28523935 | 0.87 | CDK4 (0.47) | CDK4CCND3CCND1CDK2CCNE1 | |
| SCHEMBL19711678 | 0.86 | CDK4 (0.51) | CDK4CCND3CCND1CDK2CCNE1 | |
| SCHEMBL1988950 | 0.85 | CDK4 (0.52) | CDK4CCND3CCND1CDK2CCNE1 | |
| SCHEMBL1991171 | 0.85 | CDK4 (0.50) | CDK4CCND3CCND1CDK2CCNE1 | |
| SCHEMBL22174830 | 0.85 | CDK4 (0.49) | CDK4CCND3CCND1CDK2CCNE1 | |
| SCHEMBL22174831 | 0.83 | CDK4 (0.50) | CDK4CCND3CCND1CDK2CCNE1 | |
| SCHEMBL1976455 | 0.83 | CDK4 (0.52) | CDK4CCND3CCND1CDK2CCNE1 | |
| SCHEMBL38652219 | 0.83 | CDK4 (0.52) | CDK4CCND3CCND1CDK2CCNE1 | |
| SCHEMBL29988033 | 0.83 | CDK4 (0.67) | CDK4CCND3CCND1CDK2CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119119053-A | Rabociclib middle Process for the preparation of intermediates | 天津法莫西医药科技有限公司 | 2024-12-13 | — | — | CN | disclosed |