SCHEMBL3137273

SCHEMBL3137273

CC(=O)Oc1c(O)ccc(O)c1OC(C)=O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PREP P48147 4/20 0.50
KDM4E B2RXH2 2/20 0.50
HSD17B10 Q99714 2/20 0.50
CELA1 Q9UNI1 2/20 0.50
HTT P42858 2/20 0.50
MAPT P10636 2/20 0.50
TP53 P04637 1/20 0.50
GAA P10253 1/20 0.50
PIM1 P11309 1/20 0.47
LMNA P02545 1/20 0.44
MAPK1 P28482 1/20 0.44
ALDH1A1 P00352 1/20 0.44
HPGD P15428 1/20 0.44
CYP3A4 P08684 1/20 0.43
KDR P35968 1/20 0.43
BACE1 P56817 1/20 0.42
PDE4A P27815 1/20 0.42
PDE4B Q07343 1/20 0.42
PDE4C Q08493 1/20 0.42
PDE4D Q08499 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7093557 0.85 KDM4E (0.52) PREPKDM4EHSD17B10CELA1HTT
SCHEMBL10394800 0.83 PIM1 (0.51) PREPKDM4EHSD17B10CELA1HTT
SCHEMBL24436819 0.81 KDM4E (0.41) PREPKDM4EHSD17B10CELA1HTT
SCHEMBL225923 0.81 KDM4E (0.41) PREPKDM4EHSD17B10CELA1HTT
SCHEMBL6155011 0.81 CYP3A4 (0.45) PREPKDM4EHSD17B10CELA1HTT
SCHEMBL5675873 0.78 KDM4E (0.54) KDM4EHSD17B10HTTMAPTTP53
SCHEMBL10808312 0.78 MAPK1 (0.62) KDM4EHSD17B10HTTMAPTTP53
SCHEMBL28276795 0.78 KDM4E (0.50) PREPKDM4EHSD17B10CELA1HTT
SCHEMBL2047863 0.78 KDM4E (0.62) PREPKDM4EHSD17B10CELA1HTT
SCHEMBL10632165 0.77 KDM4E (0.47) PREPKDM4EHSD17B10CELA1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104607066-A Polyamide reverse osmosis composite membrane and preparation method thereof CHINA PETROLEUM & CHEMICAL 2015-05-13 CN claimed
JP-7173270-A None JP disclosed
JP-5039348-A None JP disclosed
US-7641814-B2 polyesterether copolymer contains monomers of p- and m-phenylenedicarboxylic acid, ethylene glycol, dihydroxybiphenyl/4,4*-/, p-hydroxybenzoic acid, 6-hydroxynaphthalenecarboxyic acid; oxygen barrier property; optical clarity, lower surface roughness; packaging applications including pouches and bags E.I. DU PONT DE NEMOURS AND COMPANY (US) 2010-01-05 US disclosed
EP-1521793-B1 LIQUID CRYSTALLINE POLYMERS, PROCESSES FOR THEIR MANUFACTURE, AND ARTICLES THEREOF DU PONT (US) 2009-06-17 EP disclosed
WO-2007005429-A2 LIQUID CRYSTALLINE POLYMER BARRIER RESIN FILMS AND PROCESSES THEREOF E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-01-11 WO disclosed
US-20070003710-A1 Liquid crystalline polymer barrier resin films and processes thereof PERFORMANCE MATERIALS NA, INC. 2007-01-04 US disclosed
US-7105106-B2 Liquid crystalline polymers, processes for their manufacture, and articles thereof E. I. DU PONT DE NEMOUR AND COMPANY (US) 2006-09-12 US disclosed
EP-1521793-A1 LIQUID CRYSTALLINE POLYMERS, PROCESSES FOR THEIR MANUFACTURE, AND ARTICLES THEREOF E. I. du Pont de Nemours and Company (US) 2005-04-13 EP disclosed
US-20040058092-A1 Liquid crystalline polymers, processes for their manufacture, and articles thereof PERFORMANCE MATERIALS NA, INC. 2004-03-25 US disclosed
EP-0321691-B1 PROCESS FOR PRODUCING AROMATIC POLYESTER IDEMITSU PETROCHEMICAL CO. LTD. (JP) 1993-09-29 EP disclosed
JP-H0539348-A PRODUCTION OF AROMATIC COPOLYESTER UBE IND LTD 1993-02-19 JP disclosed
EP-0335980-B1 RUBBER COMPOSITE Takeda Chemical Industries, Ltd. (JP) 1993-01-27 EP disclosed
US-4983713-A Heat resistance, melt processability POLYPLASTICS CO., LTD. (JP) 1991-01-08 US disclosed
US-4918154-A COPOLYMER OF P-HYDROXYBENZOIC ACID, 6-HYDROXYL-2-NAPHTHOIC ACID, HYDROQUINONE, RESORCINOL, TEREPHTHALIC ACID, AND ISOPHTHALIC ACID; MELT PROCESSABILITY, HEAT RESISTANCE POLYPLASTICS CO., LTD. (JP) 1990-04-17 US disclosed
EP-0196785-B1 HIGH MODULUS CHOLESTERIC LIQUID CRYSTAL POLYESTERS NIPPON OIL CO. LTD. (JP) 1990-01-10 EP disclosed
EP-0350222-A2 Polyester resin exhibiting optical anisotropy in molten state and resin composition POLYPLASTICS CO. LTD. (JP) 1990-01-10 EP disclosed
EP-0337727-A2 Polyester resin exhibiting optical anisotropy in molten state and composition thereof POLYPLASTICS CO. LTD. (JP) 1989-10-18 EP disclosed
US-4654412-A UNSATURATED MONOMERS, FIBERS, FILMS, MOLDINGS CELANESE CORPORATION (US) 1987-03-31 US disclosed
US-4652626-A TEREPHTHALIC ACID, ETHYLENE GLYCOL, P-HYDROXYBENZOIC ACID NIPPON OIL COMPANY, LIMITED (JP) 1987-03-24 US disclosed