SCHEMBL31373294

SCHEMBL31373294

O=C(O)c1cnc2c(Br)c(F)ccc2c1O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.38
EPRS1 P07814 1/20 0.38
ALB P02768 1/20 0.38
NAPRT Q6XQN6 1/20 0.37
ASPH Q12797 2/20 0.36
KDM8 Q8N371 2/20 0.36
HAVCR2 Q8TDQ0 1/20 0.35
GRIN2D O15399 1/20 0.35
GRIN2A Q12879 1/20 0.35
GRIN2B Q13224 1/20 0.35
GRIN2C Q14957 1/20 0.35
HMGB1 P09429 1/20 0.33
CXCL12 P48061 1/20 0.33
AURKA O14965 1/20 0.33
AKR1C2 P52895 1/20 0.33
AKR1C1 Q04828 1/20 0.33
PIM1 P11309 1/20 0.33
KDM4A O75164 2/20 0.33
EGLN1 Q9GZT9 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6201208 0.84 ALB (0.40) KDM4EEPRS1ALBNAPRTASPH
SCHEMBL21550215 0.84 HAVCR2 (0.40) KDM4EEPRS1NAPRTASPHKDM8
SCHEMBL15054611 0.82 KDM4E (0.41) KDM4EEPRS1ALBNAPRTASPH
SCHEMBL30071087 0.80 EPRS1 (0.38) KDM4EEPRS1NAPRTASPHKDM8
SCHEMBL21550231 0.80 EPRS1 (0.38) KDM4EEPRS1NAPRTASPHKDM8
SCHEMBL20154297 0.80 EPRS1 (0.38) KDM4EEPRS1NAPRTASPHKDM8
SCHEMBL21550234 0.80 MAPT (0.47) KDM4ERAB9AALDH1A1HPGD
SCHEMBL6198659 0.78 ALB (0.51) KDM4EALBNAPRTASPHKDM8
SCHEMBL27350687 0.77 ALB (0.34) KDM4EEPRS1ALBNAPRTASPH
SCHEMBL29281915 0.76 HAVCR2 (0.37) KDM4EEPRS1ASPHKDM8HAVCR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025027117-A1 CARBOXAMIDE-4-QUINOLINE COMPOUNDS WITH ANTHELMINTIC ACTIVITY INTERVET INTERNATIONAL B.V. (NL) 2025-02-06 WO disclosed