SCHEMBL3137345

SCHEMBL3137345

C=Cc1cccc(N(C)C)c1C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.40
KDM4E B2RXH2 4/20 0.40
GAA P10253 4/20 0.40
ALDH1A1 P00352 5/20 0.35
ESR2 Q92731 1/20 0.35
TP53 P04637 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
LMNA P02545 2/20 0.33
PLEC Q15149 1/20 0.33
GSK3B P49841 1/20 0.33
TSHR P16473 2/20 0.32
NSD2 O96028 1/20 0.32
EGFR P00533 1/20 0.32
MAPK1 P28482 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
MCL1 Q07820 1/20 0.32
CHEK1 O14757 1/20 0.31
NEK2 P51955 1/20 0.31
LIMK1 P53667 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29558930 0.80 ALDH1A1 (0.44) MAPTKDM4EGAAALDH1A1TP53
SCHEMBL81306 0.80 ALDH1A1 (0.44) MAPTKDM4EGAAALDH1A1TP53
SCHEMBL168234 0.80 BRD4 (0.35) ALDH1A1ESR2TP53TDP1
SCHEMBL6427634 0.79 ALDH1A1 (0.46) ALDH1A1ESR2TP53TDP1LMNA
SCHEMBL1984593 0.79 ALDH1A1 (0.45) MAPTKDM4EGAAALDH1A1TP53
Hydrochloric Acid SCHEMBL9225051 0.78 ALDH1A1 (0.43) MAPTKDM4EGAAALDH1A1TP53
SCHEMBL5642052 0.77 MAPT (0.55) MAPTKDM4EGAAALDH1A1TP53
SCHEMBL28351217 0.76 MAPT (0.38) MAPTKDM4EGAAALDH1A1TP53
SCHEMBL8059223 0.75 KDM4E (0.36) MAPTKDM4EGAAALDH1A1TDP1
Boric Acid SCHEMBL30209318 0.73 ALDH1A1 (0.39) MAPTKDM4EGAAALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109689054-A Antimicrobial polymers for ophthalmic implants 克拉梅德有限公司 2019-04-26 CN claimed
CN-101217935-B Keratotic plug remover composition KAO CORP 2012-04-18 CN claimed
CN-1155287-A Cross-linked polymers for removing bile salts from patient GELTEX PHARMA INC (US) 1997-07-23 CN claimed
EP-3639066-B1 CELL GROWTH INHIBITING COPOLYMER FOR USE IN OPHTHALMIC IMPLANTS SHIUEY YICHIEH (US) 2025-10-29 EP disclosed
CN-114016002-B Antibacterial composite coating with self-regeneration function and preparation method thereof 宁波摩华科技有限公司 2024-06-14 CN disclosed
CN-114832849-A Method for fixing free radical and application 浙江大学 2022-08-02 CN disclosed
US-11185609-B2 Cell growth inhibiting copolymer for use in ophthalmic implants KeraMed, Inc. (US) 2021-11-30 US disclosed
EP-3639066-A1 CELL GROWTH INHIBITING COPOLYMER FOR USE IN OPHTHALMIC IMPLANTS Shiuey, Yichieh (US) 2020-04-22 EP disclosed
EP-3315535-B1 METHOD OF PRODUCTION OF CONJUGATED DIENE RUBBER ZEON CORP (JP) 2019-11-13 EP disclosed
US-20190292289-A1 METHOD FOR PRODUCING FOR CONJUGATED-DIENE-BASED RUBBER ZEON CORPORATION (JP) 2019-09-26 US disclosed
EP-3543278-A1 METHOD FOR PRODUCING CONJUGATED-DIENE-BASED RUBBER Zeon Corporation (JP) 2019-09-25 EP disclosed
CN-1878830-A Conjugated diene rubber compositions, process for production of the same and products of crosslinking thereof ZEON CORP (JP) 2006-12-13 CN disclosed
CN-1656153-A Conjugated diene rubber, process for producing the same, and rubber composition ZEON CORP (JP) 2005-08-17 CN disclosed
CN-1555389-A Oral-use polymer and oral-use composition 花王株式会社 2004-12-15 CN disclosed
CN-1150223-C Cationic group-containing copolymer and thickener 花王株式会社 2004-05-19 CN disclosed
CN-1136855-C Cross-linked polymers for removing bile salts from patient ԭ���ø� 2004-02-04 CN disclosed
CN-1201798-A Cationic group-containing copolymer and thickener KAO CORP (JP) 1998-12-16 CN disclosed
CN-1155287-A Cross-linked polymers for removing bile salts from patient GELTEX PHARMA INC (US) 1997-07-23 CN disclosed
US-4853439-A Water-soluble complexes of water-insoluble organic compounds GAF CORPORATION (US) 1989-08-01 US disclosed
EP-0311281-A2 Water-soluble complexes of water-insoluble organic compounds GAF CHEMICALS CORPORATION (US) 1989-04-12 EP disclosed