Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | AHR | P35869 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14208058 | 0.83 | DAO (0.58) | HTR6SRD5A2KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL2005809 | 0.82 | SRD5A2 (0.54) | HTR6SRD5A2KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL2422895 | 0.79 | SRD5A2 (0.46) | HTR6SRD5A2KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL2008256 | 0.78 | SRD5A2 (0.59) | HTR6SRD5A2KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL30147477 | 0.77 | KDM4E (0.58) | HTR6SRD5A2KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL22395238 | 0.77 | KDM4E (0.58) | HTR6SRD5A2KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL2003801 | 0.76 | HTR6 (0.50) | HTR6SRD5A2KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL2008852 | 0.76 | SRD5A2 (0.56) | HTR6SRD5A2KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL2004308 | 0.76 | SRD5A2 (0.56) | HTR6SRD5A2KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL1144792 | 0.75 | SRD5A2 (0.71) | SRD5A2KDM4EHSD17B10ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010065310-A1 | INHIBITORS OF DIACYLGLYCEROL ACYLTRANSFERASE | VIA PHARMACEUTICALS, INC (US) | 2010-06-10 | — | — | WO | disclosed |