Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 4/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CLK1 | P49759 | 1/20 | 0.47 |
| ▸ | UBE2N | P61088 | 1/20 | 0.47 |
| ▸ | CDC7 | O00311 | 4/20 | 0.45 |
| ▸ | DBF4 | Q9UBU7 | 3/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31374396 | 0.92 | LDHA (0.72) | LDHAGAAALDH1A1MAPTMEN1 | |
| SCHEMBL31374435 | 0.92 | LDHA (0.59) | LDHAGAAALDH1A1MAPTMEN1 | |
| SCHEMBL31374386 | 0.90 | LDHA (0.58) | LDHAGAAALDH1A1MAPTMEN1 | |
| SCHEMBL31374400 | 0.90 | LDHA (0.57) | LDHAGAAALDH1A1MAPTMEN1 | |
| SCHEMBL31374395 | 0.90 | LDHA (0.57) | LDHAGAAALDH1A1MAPTMEN1 | |
| SCHEMBL31374346 | 0.89 | CHEK1 (0.56) | LDHAGAAALDH1A1MAPTMEN1 | |
| SCHEMBL31374380 | 0.87 | LDHA (0.54) | LDHAGAAALDH1A1MAPTMEN1 | |
| SCHEMBL31374402 | 0.86 | GAA (0.55) | LDHAGAAALDH1A1MAPTMEN1 | |
| SCHEMBL31374453 | 0.85 | LDHA (0.57) | LDHAGAAALDH1A1MAPTMEN1 | |
| SCHEMBL1549091 | 0.80 | LDHA (0.60) | LDHAGAAALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119192171-A | Small molecule compounds and their use in vitro expansion of hematopoietic stem cells and/or progenitor cells | 上海交通大学医学院 | 2024-12-27 | — | — | CN | disclosed |