SCHEMBL31374355

SCHEMBL31374355

CCOC(=O)c1cnc(NN)s1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDC7 O00311 2/20 0.54
DBF4 Q9UBU7 2/20 0.54
AURKA O14965 1/20 0.42
AURKB Q96GD4 1/20 0.42
CDK1 P06493 2/20 0.42
CDK4 P11802 2/20 0.42
CCNE1 P24864 2/20 0.42
CDK2 P24941 2/20 0.42
ALDH1A1 P00352 7/20 0.41
MAPT P10636 4/20 0.41
SMN1; SMN2 Q16637 3/20 0.41
HPGD P15428 3/20 0.41
GAA P10253 2/20 0.41
HDAC3 O15379 1/20 0.41
HDAC4 P56524 1/20 0.41
HDAC1 Q13547 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41
KDM4E B2RXH2 3/20 0.40
PKM P14618 2/20 0.40
CCNB2 O95067 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12291072 0.86 CDC7 (0.55) CDC7DBF4AURKAAURKBCDK1
SCHEMBL23334312 0.84 CDC7 (0.54) CDC7DBF4AURKAAURKBCDK1
SCHEMBL23388184 0.83 FFAR2 (0.48) ALDH1A1MAPTSMN1; SMN2HPGDGAA
SCHEMBL16113496 0.83 CCNE1 (0.60) CDC7DBF4CDK1CDK4CCNE1
SCHEMBL7144224 0.82 CDC7 (0.49) CDC7DBF4AURKAAURKBCDK1
SCHEMBL14185028 0.82 CDC7 (0.51) CDC7DBF4AURKAAURKBCDK1
Hydrochloric Acid SCHEMBL10957492 0.81 CDC7 (0.48) CDC7DBF4AURKAAURKBCDK1
SCHEMBL21369570 0.81 CDC7 (0.50) CDC7DBF4AURKAAURKBCDK1
SCHEMBL21369463 0.81 CDC7 (0.50) CDC7DBF4AURKAAURKBCDK1
SCHEMBL21445175 0.80 CDC7 (0.49) CDC7DBF4AURKAAURKBCDK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025132754-A1 PESTICIDALLY ACTIVE QUINAZOLINE COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2025-06-26 WO disclosed
WO-2025132758-A1 PESTICIDALLY ACTIVE QUINAZOLINE COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2025-06-26 WO disclosed
CN-119192171-A Small molecule compounds and their use in vitro expansion of hematopoietic stem cells and/or progenitor cells 上海交通大学医学院 2024-12-27 CN disclosed