Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | TYK2 | P29597 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | HSPA9 | P38646 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.35 |
| ▸ | PDE2A | O00408 | 6/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | BCDIN3D | Q7Z5W3 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.33 |
| ▸ | LIPC | P11150 | 1/20 | 0.33 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.33 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.33 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27035563 | 1.00 | AKR1C3 (0.41) | AKR1C3AKR1C2JAK2JAK1TYK2 | |
| SCHEMBL27035553 | 0.89 | AKR1C3 (0.42) | AKR1C3AKR1C2JAK2JAK1TYK2 | |
| SCHEMBL27067091 | 0.87 | AKR1C3 (0.42) | AKR1C3AKR1C2JAK2JAK1TYK2 | |
| SCHEMBL30683308 | 0.82 | JAK2 (0.39) | AKR1C3AKR1C2JAK2JAK1TYK2 | |
| SCHEMBL27035626 | 0.82 | JAK2 (0.39) | AKR1C3AKR1C2JAK2JAK1TYK2 | |
| SCHEMBL27035554 | 0.77 | JAK2 (0.38) | AKR1C3AKR1C2JAK2JAK1TYK2 | |
| SCHEMBL30683313 | 0.75 | TEAD1 (0.37) | AKR1C3AKR1C2JAK2JAK1TYK2 | |
| SCHEMBL27035687 | 0.75 | TEAD1 (0.37) | AKR1C3AKR1C2JAK2JAK1TYK2 | |
| SCHEMBL27035562 | 0.75 | JAK2 (0.39) | AKR1C3AKR1C2JAK2JAK1TYK2 | |
| SCHEMBL27035651 | 0.75 | JAK1 (0.42) | JAK2JAK1TYK2JAK3HSPA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119497708-A | TEAD inhibitors and methods of use | 思博睿生物探索公司 | 2025-02-21 | — | — | CN | disclosed |