Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.34 |
| ▸ | ATM | Q13315 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 4/20 | 0.32 |
| ▸ | FAAH | O00519 | 3/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 7/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31374736 | 0.85 | FOLH1 (0.41) | NPSR1FOLH1MGLLFAAHPTGS1 | |
| SCHEMBL22207235 | 0.83 | AKT1 (0.45) | AKT1TDP1ATMNPSR1MEN1 | |
| SCHEMBL22207234 | 0.83 | AKT1 (0.45) | AKT1TDP1ATMNPSR1MEN1 | |
| SCHEMBL28620369 | 0.82 | AKT1 (0.41) | AKT1TDP1ATMNPSR1MEN1 | |
| SCHEMBL28624848 | 0.82 | AKT1 (0.41) | AKT1TDP1ATMNPSR1MEN1 | |
| SCHEMBL31374703 | 0.81 | FOLH1 (0.34) | AKT1FOLH1PTGS1PTGS2 | |
| Trifluoroacetic Acid SCHEMBL22207652 | 0.77 | AKT1 (0.43) | AKT1TDP1ATMNPSR1MEN1 | |
| Trifluoroacetic Acid SCHEMBL22207651 | 0.77 | AKT1 (0.43) | AKT1TDP1ATMNPSR1MEN1 | |
| SCHEMBL18942764 | 0.75 | AKT1 (0.52) | AKT1TDP1ATMNPSR1MGLL | |
| SCHEMBL23113662 | 0.75 | AKT1 (0.48) | AKT1MEN1KMT2AFOLH1PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113301920-B | Complexes comprising a ligand, a spacer, a peptide linker and a biomolecule | 安斯泰来制药株式会社 | 2025-01-14 | — | — | CN | disclosed |