Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.55 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14227400 | 0.81 | CYP1A2 (0.52) | KDM4EHSP90AA1TDP1ALDH1A1HPGD | |
| SCHEMBL8626651 | 0.81 | HSP90AA1 (0.46) | NR4A2KDM4EHSP90AA1HSP90AB1ALDH1A1 | |
| SCHEMBL12424714 | 0.79 | ADORA2A (0.48) | NCF1NR4A2ADORA2AADORA1KDM4E | |
| SCHEMBL13968415 | 0.78 | HTT (0.44) | KDM4EHSP90AA1HSP90AB1LMNARAB9A | |
| SCHEMBL20468588 | 0.78 | ALDH1A1 (0.43) | KDM4EHSP90AA1TDP1ALDH1A1HPGD | |
| SCHEMBL13968416 | 0.78 | MAPT (0.49) | NR4A2ADORA1KDM4EHSP90AA1TDP1 | |
| SCHEMBL31354830 | 0.78 | HSP90AA1 (0.43) | KDM4EHSP90AA1TDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL28183220 | 0.77 | HSP90AA1 (0.40) | NCF1NR4A2HSP90AA1HSP90AB1HPGD | |
| SCHEMBL13622758 | 0.76 | ADORA1 (0.64) | NCF1NR4A2ADORA2AADORA1KDM4E | |
| SCHEMBL20009341 | 0.75 | PIP4K2C (0.40) | KDM4EHSP90AA1ALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114621222-B | 6-6 Fused bicyclic heteroaryl compounds and their use as LATS inhibitors | 诺华股份有限公司 | 2024-12-17 | — | — | CN | claimed |