Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 5/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | UBE2N | P61088 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | LIPE | Q05469 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11647126 | 1.00 | APP (0.56) | APPFFAR1MAPTMAPK1TDP1 | |
| SCHEMBL1421536 | 0.90 | APP (0.68) | APPMAPK1KMT2AHTR1AKDM4E | |
| SCHEMBL6830402 | 0.90 | APP (0.68) | APPMAPTKMT2AHTR1AKDM4E | |
| SCHEMBL28843836 | 0.87 | FFAR1 (0.59) | APPFFAR1MAPTMAPK1TDP1 | |
| SCHEMBL23981776 | 0.85 | PDE4B (0.44) | APPFFAR1MAPTMAPK1TDP1 | |
| SCHEMBL20456105 | 0.85 | RXRA (0.52) | APPFFAR1MAPTMAPK1TDP1 | |
| SCHEMBL30712297 | 0.84 | C5AR1 (0.52) | APPC5AR1HTR1ADRD2 | |
| SCHEMBL17685895 | 0.84 | APP (0.65) | APPFFAR1MAPTMAPK1TDP1 | |
| SCHEMBL20576395 | 0.84 | APP (0.49) | APPFFAR1MAPTMAPK1TDP1 | |
| SCHEMBL646914 | 0.84 | APP (0.65) | APPFFAR1MAPTMAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119431212-A | Synthesis method of 7-bromo-5, 6-bis (benzyloxy) benzopyrrole and derivative dimer thereof | 中国科学院生物物理研究所 | 2025-02-14 | — | — | CN | disclosed |