Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 4/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31628240 | 1.00 | BDKRB1 (0.35) | BDKRB1HDAC6HDAC1HDAC8GAA | |
| SCHEMBL26962612 | 0.86 | HDAC6 (0.38) | BDKRB1HDAC6HDAC1HDAC8GAA | |
| SCHEMBL29797029 | 0.86 | HDAC6 (0.38) | BDKRB1HDAC6HDAC1HDAC8GAA | |
| SCHEMBL31628095 | 0.86 | GAA (0.36) | BDKRB1HDAC6HDAC1HDAC8GAA | |
| SCHEMBL31628116 | 0.85 | GAA (0.37) | BDKRB1HDAC6HDAC1HDAC8GAA | |
| SCHEMBL31375596 | 0.85 | GAA (0.37) | BDKRB1HDAC6HDAC1HDAC8GAA | |
| SCHEMBL31375533 | 0.85 | HDAC6 (0.40) | BDKRB1HDAC6HDAC1HDAC8GAA | |
| SCHEMBL31628392 | 0.85 | HDAC6 (0.40) | BDKRB1HDAC6HDAC1HDAC8GAA | |
| SCHEMBL30830371 | 0.83 | HDAC6 (0.40) | BDKRB1HDAC6HDAC1HDAC8GAA | |
| SCHEMBL26962169 | 0.81 | HDAC6 (0.39) | BDKRB1HDAC6HDAC1HDAC8GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119677733-A | Bicyclic tetrahydrothiazepine derivatives | 豪夫迈·罗氏有限公司 | 2025-03-21 | — | — | CN | disclosed |