Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | BDKRB1 | P46663 | 4/20 | 0.34 |
| ▸ | PLAT | P00750 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31375533 | 1.00 | HDAC6 (0.40) | HDAC6HDAC1HDAC8HDAC4HDAC5 | |
| SCHEMBL26962612 | 0.91 | HDAC6 (0.38) | HDAC6HDAC1HDAC8HDAC4HDAC5 | |
| SCHEMBL29797029 | 0.91 | HDAC6 (0.38) | HDAC6HDAC1HDAC8HDAC4HDAC5 | |
| SCHEMBL30830371 | 0.91 | HDAC6 (0.40) | HDAC6HDAC1HDAC8HDAC4HDAC5 | |
| SCHEMBL31628095 | 0.91 | GAA (0.36) | HDAC6HDAC1HDAC8HDAC4HDAC5 | |
| SCHEMBL26962169 | 0.90 | HDAC6 (0.39) | HDAC6HDAC1HDAC8HDAC4HDAC5 | |
| SCHEMBL31628116 | 0.86 | GAA (0.37) | HDAC6HDAC1HDAC8HDAC4HDAC5 | |
| SCHEMBL31375596 | 0.86 | GAA (0.37) | HDAC6HDAC1HDAC8HDAC4HDAC5 | |
| SCHEMBL31628240 | 0.85 | BDKRB1 (0.35) | HDAC6HDAC1HDAC8HDAC4HDAC5 | |
| SCHEMBL31375592 | 0.85 | BDKRB1 (0.35) | HDAC6HDAC1HDAC8HDAC4HDAC5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568959-A1 | BICYCLIC TETRAHYDROTHIAZEPINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2025-06-18 | — | — | EP | disclosed |