Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 7/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | BDKRB1 | P46663 | 3/20 | 0.34 |
| ▸ | BRD4 | O60885 | 3/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31628274 | 1.00 | KIT (0.40) | KITGAAHDAC6HDAC4BDKRB1 | |
| SCHEMBL31628231 | 0.87 | KIT (0.39) | KITHDAC6HDAC4BDKRB1 | |
| SCHEMBL31628116 | 0.87 | GAA (0.37) | KITGAAHDAC6HDAC4BDKRB1 | |
| SCHEMBL31375596 | 0.87 | GAA (0.37) | KITGAAHDAC6HDAC4BDKRB1 | |
| SCHEMBL31628193 | 0.77 | GAA (0.34) | KITGAABRD4 | |
| SCHEMBL31375572 | 0.77 | GAA (0.34) | KITGAABRD4 | |
| SCHEMBL20264133 | 0.75 | SMN1; SMN2 (0.48) | GAAHDAC6EPHX2ALOX15HDAC1 | |
| SCHEMBL31375549 | 0.74 | GAA (0.37) | GAABRD4EPHX2HDAC1 | |
| SCHEMBL31375540 | 0.74 | GAA (0.37) | GAAHDAC6BRD4EPHX2 | |
| SCHEMBL31628170 | 0.74 | GAA (0.37) | GAAHDAC6BRD4EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119677733-A | Bicyclic tetrahydrothiazepine derivatives | 豪夫迈·罗氏有限公司 | 2025-03-21 | — | — | CN | disclosed |