Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 20/20 | 0.81 |
| ▸ | WDR77 | Q9BQA1 | 20/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23087601 | 0.89 | PRMT5 (1.00) | PRMT5WDR77 | |
| SCHEMBL29735220 | 0.89 | PRMT5 (1.00) | PRMT5WDR77 | |
| SCHEMBL29735209 | 0.89 | PRMT5 (1.00) | PRMT5WDR77 | |
| SCHEMBL23087171 | 0.89 | PRMT5 (1.00) | PRMT5WDR77 | |
| SCHEMBL23099142 | 0.86 | PRMT5 (0.80) | PRMT5WDR77 | |
| SCHEMBL23087567 | 0.86 | PRMT5 (0.86) | PRMT5WDR77 | |
| SCHEMBL29735065 | 0.86 | PRMT5 (0.86) | PRMT5WDR77 | |
| SCHEMBL23087879 | 0.86 | PRMT5 (0.78) | PRMT5WDR77 | |
| SCHEMBL29735234 | 0.86 | PRMT5 (0.78) | PRMT5WDR77 | |
| SCHEMBL23087913 | 0.85 | PRMT5 (0.88) | PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119219608-A | Polycyclic derivative inhibitor, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2024-12-31 | — | — | CN | disclosed |