Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 9/20 | 0.63 |
| ▸ | WDR77 | Q9BQA1 | 9/20 | 0.63 |
| ▸ | PARP1 | P09874 | 2/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23087948 | 0.84 | PRMT5 (0.66) | PRMT5WDR77PARP1BRD4TDP1 | |
| SCHEMBL31519288 | 0.83 | PRMT5 (0.64) | PRMT5WDR77PARP1BRD4TDP1 | |
| SCHEMBL31519320 | 0.83 | PRMT5 (0.63) | PRMT5WDR77PARP1BRD4SMN1; SMN2 | |
| SCHEMBL31568857 | 0.83 | PRMT5 (0.63) | PRMT5WDR77PARP1BRD4SMN1; SMN2 | |
| SCHEMBL31380359 | 0.79 | PRMT5 (0.61) | PRMT5WDR77PARP1 | |
| SCHEMBL23087489 | 0.78 | PRMT5 (1.00) | PRMT5WDR77PARP1 | |
| SCHEMBL31540443 | 0.76 | PRMT5 (0.57) | PRMT5WDR77PARP1SMN1; SMN2 | |
| SCHEMBL23087677 | 0.75 | PRMT5 (0.72) | PRMT5WDR77 | |
| SCHEMBL29735283 | 0.75 | PRMT5 (0.72) | PRMT5WDR77 | |
| SCHEMBL31376006 | 0.74 | PRMT5 (0.51) | PRMT5WDR77PARP1BRD4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119219608-A | Polycyclic derivative inhibitor, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2024-12-31 | — | — | CN | disclosed |