Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 9/20 | 0.51 |
| ▸ | WDR77 | Q9BQA1 | 9/20 | 0.51 |
| ▸ | PARP1 | P09874 | 3/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 2/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | PDE1A | P54750 | 1/20 | 0.36 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31376007 | 0.86 | PRMT5 (0.56) | PRMT5WDR77PARP1BRD4TDP1 | |
| SCHEMBL27386026 | 0.82 | PRMT5 (0.50) | PRMT5WDR77PARP1BRD4TDP1 | |
| SCHEMBL27002206 | 0.79 | PARP1 (0.54) | PRMT5WDR77PARP1BRD4TDP1 | |
| SCHEMBL30752865 | 0.77 | PRMT5 (0.50) | PRMT5WDR77PARP1KDM4ELMNA | |
| SCHEMBL27002412 | 0.76 | PRMT5 (0.73) | PRMT5WDR77PARP1BRD4TDP1 | |
| SCHEMBL27002484 | 0.76 | PRMT5 (0.56) | PRMT5WDR77PARP1KDM4ELMNA | |
| SCHEMBL27385996 | 0.75 | PRMT5 (0.48) | PRMT5WDR77PARP1KDM4ELMNA | |
| SCHEMBL31375998 | 0.74 | PRMT5 (0.63) | PRMT5WDR77PARP1BRD4TDP1 | |
| SCHEMBL30753025 | 0.74 | PRMT5 (0.47) | PRMT5WDR77PARP1KDM4ELMNA | |
| SCHEMBL23087948 | 0.73 | PRMT5 (0.66) | PRMT5WDR77PARP1BRD4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119219608-A | Polycyclic derivative inhibitor, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2024-12-31 | — | — | CN | disclosed |