Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.47 |
| ▸ | HTR3B | O95264 | 1/20 | 0.47 |
| ▸ | HTR3A | P46098 | 1/20 | 0.47 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.47 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.47 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.46 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.46 |
| ▸ | SCN1A | P35498 | 1/20 | 0.45 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.45 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22101385 | 0.94 | CHRNA7 (0.54) | CHRNA7MEN1KMT2AHTR3EHTR3B | |
| SCHEMBL21886707 | 0.94 | CHRNA7 (0.54) | CHRNA7MEN1KMT2AHTR3EHTR3B | |
| SCHEMBL14461205 | 0.94 | CHRNA7 (0.54) | CHRNA7MEN1KMT2AHTR3EHTR3B | |
| SCHEMBL13369465 | 0.85 | CHRNA7 (0.51) | CHRNA7MEN1KMT2AHTR3EHTR3B | |
| SCHEMBL12614061 | 0.85 | CHRNA7 (0.51) | CHRNA7MEN1KMT2AHTR3EHTR3B | |
| SCHEMBL5185766 | 0.84 | KMT2A (0.59) | CHRNA7MEN1KMT2AHTR3EHTR3B | |
| SCHEMBL18670620 | 0.82 | SCN1A (0.57) | MEN1KMT2ASCN1ASCN2ASCN3A | |
| SCHEMBL28339381 | 0.81 | CHRNA7 (0.56) | CHRNA7MEN1KMT2AHTR3EHTR3B | |
| SCHEMBL4730582 | 0.78 | MEN1 (0.56) | CHRNA7MEN1KMT2AHTR3EHTR3B | |
| SCHEMBL11637921 | 0.78 | CHRNA7 (0.53) | CHRNA7MEN1KMT2AHTR3EHTR3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250032440-A1 | COMPOSITIONS AND METHODS FOR TREATING NEURODEGENERATIVE DISORDERS | NATIONAL INSTITUTES OF HEALTH | 2025-01-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250032440-A1 | COMPOSITIONS AND METHODS FOR TREATING NEURODEGENERATIVE DISORDERS | NLN, PSEN2, PSEN1 | CHRNA7 361/4885MEN1 4452/4885KMT2A 3549/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.