Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.53 |
| ▸ | PPARD | Q03181 | 2/20 | 0.53 |
| ▸ | PPARA | Q07869 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27983620 | 1.00 | PPARG (0.53) | PPARGPPARDPPARACYP3A4TSHR | |
| SCHEMBL27983345 | 1.00 | PPARG (0.53) | PPARGPPARDPPARACYP3A4TSHR | |
| SCHEMBL27983181 | 1.00 | PPARG (0.53) | PPARGPPARDPPARACYP3A4TSHR | |
| SCHEMBL14032494 | 0.81 | ALDH1A1 (0.50) | PPARGPPARDPPARAALDH1A1SMN1; SMN2 | |
| SCHEMBL7297988 | 0.81 | PPARG (0.57) | PPARGPPARDPPARACYP3A4TSHR | |
| SCHEMBL10335590 | 0.80 | PPARG (0.61) | PPARGPPARDPPARACYP3A4TSHR | |
| SCHEMBL6055371 | 0.80 | PPARG (0.61) | PPARGPPARDPPARACYP3A4TSHR | |
| SCHEMBL14032381 | 0.80 | PPARG (0.49) | PPARGPPARDPPARAALDH1A1SMN1; SMN2 | |
| SCHEMBL11661594 | 0.80 | ALDH1A1 (0.49) | PPARGPPARDPPARAALDH1A1SMN1; SMN2 | |
| SCHEMBL22785859 | 0.79 | CYP3A4 (0.74) | PPARGPPARDPPARACYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119504665-B | 2-Aryl-3-acyloxy tetrahydrofuran compound, preparation method and application thereof | 遵义医科大学 | 2025-06-10 | — | — | CN | disclosed |
| CN-119504665-A | 2-Aryl-3-acyloxy tetrahydrofuran compound, preparation method and application thereof | 遵义医科大学 | 2025-02-25 | — | — | CN | disclosed |