Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15749768 | 1.00 | BRD4 (0.36) | BRD4CREBBPDGAT1MEN1KMT2A | |
| SCHEMBL14502048 | 0.83 | MEN1 (0.38) | BRD4CREBBPDGAT1MEN1KMT2A | |
| SCHEMBL17362969 | 0.83 | BRD4 (0.38) | BRD4CREBBPDGAT1KMT2ANPC1 | |
| SCHEMBL19861615 | 0.83 | MEN1 (0.33) | MEN1KMT2AKCNH2NPC1RAB9A | |
| SCHEMBL2541707 | 0.80 | MEN1 (0.36) | BRD4CREBBPDGAT1MEN1KMT2A | |
| SCHEMBL5953458 | 0.80 | MEN1 (0.45) | BRD4DGAT1MEN1KMT2AKCNH2 | |
| SCHEMBL24344413 | 0.79 | MEN1 (0.41) | BRD4CREBBPDGAT1MEN1KMT2A | |
| SCHEMBL29534448 | 0.79 | MEN1 (0.41) | BRD4CREBBPDGAT1MEN1KMT2A | |
| SCHEMBL2321346 | 0.79 | MEN1 (0.35) | BRD4CREBBPDGAT1MEN1KMT2A | |
| SCHEMBL5951458 | 0.79 | MEN1 (0.56) | MEN1KMT2AKCNH2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119451959-A | Imidazo [4,5-C ] pyridine derivatives as SIK modulators for the treatment of rheumatoid arthritis | 豪夫迈·罗氏有限公司 | 2025-02-14 | — | — | CN | disclosed |