Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | BUB1 | O43683 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30705661 | 0.83 | KDM4E (0.42) | KDM4EHSD17B10ALDH1A1HPGDOPRM1 | |
| SCHEMBL31376591 | 0.83 | KDM4E (0.44) | KDM4EHSD17B10ALDH1A1HPGDOPRM1 | |
| SCHEMBL31376414 | 0.77 | KDM4E (0.67) | KDM4EHSD17B10ALDH1A1HPGDOPRM1 | |
| SCHEMBL30810912 | 0.77 | KDM4E (0.72) | KDM4EHSD17B10ALDH1A1HPGDTP53 | |
| SCHEMBL30705510 | 0.75 | GRIA1 (0.35) | KDM4EHSD17B10ALDH1A1HPGDBUB1 | |
| SCHEMBL31376415 | 0.75 | KDM4E (0.70) | KDM4EHSD17B10ALDH1A1HPGDTP53 | |
| Hydrochloric Acid SCHEMBL30705545 | 0.75 | — | — | |
| SCHEMBL30705553 | 0.74 | GRIA1 (0.33) | KDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL30810863 | 0.72 | KDM4E (0.47) | KDM4EHSD17B10ALDH1A1HPGDHTT | |
| SCHEMBL31376411 | 0.71 | ALDH1A1 (0.44) | KDM4EHSD17B10ALDH1A1HPGDOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119403787-A | 3- (Sulfonyl or iminosulfonyl) prop-2-en-1-yl ] -2-oxo-1, 2-dihydropyridine-3-carboxamide derivatives | 福临德治疗公司 | 2025-02-07 | — | — | CN | disclosed |