Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 17/20 | 0.56 |
| ▸ | MAP2K2 | P36507 | 7/20 | 0.48 |
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | MAP2K5 | Q13163 | 1/20 | 0.39 |
| ▸ | EIF2AK1 | Q9BQI3 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | PRKCB | P05771 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.38 |
| ▸ | STK3 | Q13188 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31135614 | 0.90 | MAP2K1 (0.59) | MAP2K1MAP2K2IDO1AURKAPRKCB | |
| SCHEMBL23851383 | 0.90 | MAP2K1 (0.59) | MAP2K1MAP2K2IDO1AURKAPRKCB | |
| SCHEMBL31403386 | 0.86 | MAP2K1 (0.52) | MAP2K1MAP2K2IDO1MAP2K5EIF2AK1 | |
| SCHEMBL23852559 | 0.86 | MAP2K1 (0.52) | MAP2K1MAP2K2IDO1MAP2K5EIF2AK1 | |
| SCHEMBL31543771 | 0.81 | MAP2K1 (0.49) | MAP2K1MAP2K2IDO1 | |
| SCHEMBL24195682 | 0.81 | DHODH (0.42) | MAP2K1MAP2K2 | |
| SCHEMBL23851097 | 0.81 | MAP2K1 (0.62) | MAP2K1MAP2K2IDO1 | |
| SCHEMBL31135615 | 0.81 | MAP2K1 (0.62) | MAP2K1MAP2K2IDO1 | |
| SCHEMBL23850846 | 0.80 | MAP2K1 (0.50) | MAP2K1MAP2K2IDO1 | |
| SCHEMBL31135631 | 0.80 | MAP2K1 (0.50) | MAP2K1MAP2K2IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113473978-B | Cyanoarene-aniline compounds for the treatment of skin disorders | 恩福莱克逊治疗有限公司 | 2025-03-28 | — | — | CN | disclosed |
| CN-119215031-A | Arylaniline and heteroaryl aniline compounds for the treatment of skin cancer | 恩福莱克逊治疗有限公司 | 2024-12-31 | — | — | CN | disclosed |