Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 11/20 | 0.52 |
| ▸ | MAP2K2 | P36507 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SYK | P43405 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAP2K5 | Q13163 | 1/20 | 0.40 |
| ▸ | EIF2AK1 | Q9BQI3 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23852559 | 1.00 | MAP2K1 (0.52) | MAP2K1MAP2K2ALDH1A1SYKKDM4E | |
| SCHEMBL31376766 | 0.86 | MAP2K1 (0.56) | MAP2K1MAP2K2MAP2K5EIF2AK1IDO1 | |
| SCHEMBL930913 | 0.85 | MAP2K1 (0.55) | MAP2K1MAP2K2SYKMAPTMAP2K5 | |
| SCHEMBL23850846 | 0.82 | MAP2K1 (0.50) | MAP2K1MAP2K2IDO1 | |
| SCHEMBL31135631 | 0.82 | MAP2K1 (0.50) | MAP2K1MAP2K2IDO1 | |
| SCHEMBL24195795 | 0.79 | MAP2K1 (0.65) | MAP2K1MAP2K2MAP2K5EIF2AK1 | |
| SCHEMBL23851383 | 0.76 | MAP2K1 (0.59) | MAP2K1MAP2K2IDO1 | |
| SCHEMBL31135614 | 0.76 | MAP2K1 (0.59) | MAP2K1MAP2K2IDO1 | |
| SCHEMBL24196093 | 0.75 | MAP2K1 (0.41) | MAP2K1MAP2K2IDO1 | |
| SCHEMBL929220 | 0.75 | MAP2K1 (0.43) | MAP2K1MAP2K2MAP2K5EIF2AK1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3883552-B1 | CYANOARYL-ANILINE COMPOUNDS FOR TREATMENT OF DERMAL DISORDERS | NFLECTION THERAPEUTICS INC (US) | 2025-04-09 | — | — | EP | claimed |
| CN-113473978-B | Cyanoarene-aniline compounds for the treatment of skin disorders | 恩福莱克逊治疗有限公司 | 2025-03-28 | — | — | CN | disclosed |