SCHEMBL31377196

SCHEMBL31377196

COc1ccc(C[C@@H]2[C@H](OC(=O)C(C)C)[C@@H](OC(=O)OC(C)(C)C)CN2C(=O)OC(C)(C)C)cc1

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 3/20 0.40
▸ LMNA P02545 3/20 0.40
▸ MEN1 O00255 1/20 0.36
▸ KMT2A Q03164 1/20 0.36
▸ CACNA1B Q00975 1/20 0.36
▸ L3MBTL1 Q9Y468 1/20 0.35
▸ TACR1 P25103 4/20 0.35
▸ SMN1; SMN2 Q16637 2/20 0.35
▸ MAPT P10636 1/20 0.35
▸ GHSR Q92847 1/20 0.34
▸ POLB P06746 1/20 0.34
▸ PKM P14618 1/20 0.34
▸ TP53 P04637 2/20 0.34
▸ BMP1 P13497 1/20 0.34
▸ CCR3 P51677 1/20 0.34
▸ CYP2D6 P10635 1/20 0.33
▸ MAPK1 P28482 1/20 0.33
▸ HIF1A Q16665 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31377156 0.90 CACNA1B (0.40) ALDH1A1LMNAMEN1KMT2ACACNA1B
SCHEMBL31377328 0.89 SMN1; SMN2 (0.43) ALDH1A1LMNAMEN1KMT2AL3MBTL1
SCHEMBL31377355 0.88 ALDH1A1 (0.37) ALDH1A1LMNAMEN1KMT2ACACNA1B
SCHEMBL31421133 0.87 ALDH1A1 (0.40) ALDH1A1LMNAMEN1KMT2ACACNA1B
SCHEMBL31377165 0.87 ALDH1A1 (0.36) ALDH1A1LMNAMEN1KMT2ACACNA1B
SCHEMBL31377090 0.87 ALDH1A1 (0.37) ALDH1A1LMNAMEN1KMT2ACACNA1B
SCHEMBL31377309 0.86 ALDH1A1 (0.36) ALDH1A1LMNAMEN1KMT2ACACNA1B
SCHEMBL32687577 0.86 ALDH1A1 (0.37) ALDH1A1LMNAMEN1KMT2ACACNA1B
SCHEMBL31377340 0.85 ALDH1A1 (0.39) ALDH1A1LMNAMEN1KMT2ASMN1; SMN2
SCHEMBL31377106 0.85 ALDH1A1 (0.39) ALDH1A1LMNAMEN1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025064683-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2025-03-27 — — WO disclosed
US-20250091989-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS Interdict Bio, Inc. (US) 2025-03-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250091989-A1 SMALL MOLECULE PROTEIN SYNTHESIS MODULATORS MYC, KRAS, NRAS ALDH1A1 2774/4885LMNA 2869/4885MEN1 867/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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