Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.42 |
| ▸ | DPP3 | Q9NY33 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 7/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | XIAP | P98170 | 1/20 | 0.38 |
| ▸ | MLX | Q9UH92 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | CPA1 | P15085 | 1/20 | 0.37 |
| ▸ | CPA2 | P48052 | 1/20 | 0.37 |
| ▸ | CPA4 | Q9UI42 | 1/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.37 |
| ▸ | PREP | P48147 | 1/20 | 0.37 |
| ▸ | FAP | Q12884 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13299859 | 1.00 | DPP4 (0.42) | DPP4DPP3ELANESLC6A2XIAP | |
| Hydrochloric Acid SCHEMBL3257601 | 0.99 | DPP4 (0.42) | DPP4DPP3ELANESLC6A2XIAP | |
| Hydrochloric Acid SCHEMBL3257603 | 0.99 | DPP4 (0.42) | DPP4DPP3ELANESLC6A2XIAP | |
| Hydrochloric Acid SCHEMBL3257602 | 0.99 | DPP4 (0.42) | DPP4DPP3ELANESLC6A2XIAP | |
| Trifluoroacetic Acid SCHEMBL3255535 | 0.95 | ELANE (0.44) | DPP4DPP3ELANEDPP7 | |
| Trifluoroacetic Acid SCHEMBL3255537 | 0.95 | ELANE (0.44) | DPP4DPP3ELANEDPP7 | |
| SCHEMBL3255539 | 0.85 | ELANE (0.41) | DPP4DPP3ELANE | |
| SCHEMBL13299858 | 0.82 | DPP4 (0.39) | DPP4DPP3ELANEXIAPDPP7 | |
| SCHEMBL13299868 | 0.82 | DPP4 (0.39) | DPP4DPP3ELANEXIAPDPP7 | |
| SCHEMBL6860338 | 0.82 | ELANE (0.51) | DPP4DPP3ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010065461-A1 | TRI-PEPTIDE INHIBITORS OF SERINE ELASTASES | ACCUTHERA, INC. (US) | 2010-06-10 | — | — | WO | disclosed |