Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 14/20 | 0.51 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.40 |
| ▸ | DPP3 | Q9NY33 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13299859 | 0.82 | DPP4 (0.42) | ELANEDPP3DPP4 | |
| SCHEMBL3137758 | 0.82 | DPP4 (0.42) | ELANEDPP3DPP4 | |
| Hydrochloric Acid SCHEMBL3257602 | 0.81 | DPP4 (0.42) | ELANEDPP3DPP4 | |
| Hydrochloric Acid SCHEMBL3257603 | 0.81 | DPP4 (0.42) | ELANEDPP3DPP4 | |
| Hydrochloric Acid SCHEMBL3257601 | 0.81 | DPP4 (0.42) | ELANEDPP3DPP4 | |
| Trifluoroacetic Acid SCHEMBL3255537 | 0.78 | ELANE (0.44) | ELANEDPP3DPP4 | |
| Trifluoroacetic Acid SCHEMBL3255535 | 0.78 | ELANE (0.44) | ELANEDPP3DPP4 | |
| SCHEMBL7286287 | 0.78 | ELANE (0.46) | ELANEHCRTR1HCRTR2DPP4 | |
| SCHEMBL7280248 | 0.78 | ELANE (0.46) | ELANEHCRTR1HCRTR2DPP4 | |
| SCHEMBL27329037 | 0.78 | ELANE (0.46) | ELANEHCRTR1HCRTR2DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6835714-B1 | Heterocyclic compounds, intermediates thereof and elastase inhibitors | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 2004-12-28 | — | — | US | disclosed |
| EP-1157998-A1 | HETEROCYCLIC COMPOUNDS, INTERMEDIATES THEREOF AND ELASTASE INHIBITORS | Dainippon Pharmaceutical Co., Ltd. (JP) | 2001-11-28 | — | — | EP | disclosed |