⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28554005 | 0.79 | ALDH1A1 (0.50) | — | |
| SCHEMBL20547682 | 0.72 | — | — | |
| Teflurane SCHEMBL566553 | 0.70 | — | — | |
| Teflurane SCHEMBL10432101 | 0.67 | ALDH1A1 (0.47) | — | |
| SCHEMBL28566567 | 0.67 | — | — | |
| SCHEMBL28524996 | 0.67 | — | — | |
| SCHEMBL11591664 | 0.67 | — | — | |
| SCHEMBL8899596 | 0.65 | — | — | |
| SCHEMBL865243 | 0.65 | — | — | |
| SCHEMBL28533661 | 0.65 | ALDH1A1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108101739-B | Method for continuously preparing 3,3, 3-trifluoro-1, 2-propanediol | 西安近代化学研究所 | 2021-04-13 | — | — | CN | claimed |
| CN-108101739-A | The continuous method for preparing tri- fluoro- 1,2- propylene glycol of 3,3,3- | 西安近代化学研究所 | 2018-06-01 | — | — | CN | claimed |
| CN-108101739-B | Method for continuously preparing 3,3, 3-trifluoro-1, 2-propanediol | 西安近代化学研究所 | 2021-04-13 | — | — | CN | disclosed |
| CN-108101739-A | The continuous method for preparing tri- fluoro- 1,2- propylene glycol of 3,3,3- | 西安近代化学研究所 | 2018-06-01 | — | — | CN | disclosed |
| US-8338355-B2 | Azeotrope or azeotrope-like composition comprising 1,1,2,2-tetrafluoro-1-methoxyethane | CENTRAL GLASS COMPANY, LIMITED (JP) | 2012-12-25 | — | — | US | disclosed |
| EP-1628944-B1 | PROCESS FOR THE REDUCTION OF ACIDIC CONTAMINANTS IN FLUORINATED HYDROCARBONS | DU PONT (US) | 2012-10-31 | — | — | EP | disclosed |
| US-8212092-B2 | Reducing concentration of hydrofluoric, hydrochloric, hydrobromic, hydroiodic, nitric, and sulfuric acids in fluorinated hydrocarbons by contacting hydrocarbons with phosphorous oxyacid salt such as orthophosphoric acid, phosphorous acid, metaphosphoric acid, and pyrophosphoric acid salts | E I DU PONT DE NEMOURS AND COMPANY (US) | 2012-07-03 | — | — | US | disclosed |
| US-20100004155-A1 | Azeotrope or Azeotrope-Like Composition Comprising 1,1,2,2-tetrafluoro-1-methoxyethane | CENTRAL GLASS COMPANY LIMITED (JP) | 2010-01-07 | — | — | US | disclosed |
| US-20080255396-A1 | PROCESS FOR THE REDUCTION OF ACIDIC CONTAMINATES IN FLUORINATED HYDROCARBONS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-10-16 | — | — | US | disclosed |
| US-7405334-B2 | Process for the reduction of acidic contaminates in fluorinated hydrocarbons | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-07-29 | — | — | US | disclosed |
| US-20060266976-A1 | Compositions comprising bromofluoro-olefins and uses thereof | E. I. DU PONT DE NEMOURS AND COMPANY | 2006-11-30 | — | — | US | disclosed |
| EP-1628944-A2 | PROCESS FOR THE REDUCTION OF ACIDIC CONTAMINANTES IN FLUORINATED HYDROCARBONS | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2006-03-01 | — | — | EP | disclosed |
| WO-2004106272-A2 | PROCESS FOR THE REDUCTION OF ACIDIC CONTAMINANTES IN FLUORINATED HYDROCARBONS | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2004-12-09 | — | — | WO | disclosed |
| US-20040236161-A1 | Process for the reduction of acidic contaminates in fluorinated hydrocarbons | E. I. DU PONT DE NAMOURS AND COMPANY | 2004-11-25 | — | — | US | disclosed |