Fluoride

Fluoride

SCHEMBL31379741

Cn1c(S)nc2ccccc21.F

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.60
SMN1; SMN2 Q16637 7/20 0.59
RAB9A P51151 8/20 0.50
NPC1 O15118 7/20 0.50
LMNA P02545 2/20 0.50
KDM4E B2RXH2 8/20 0.49
ALDH1A1 P00352 6/20 0.49
KMT2A Q03164 2/20 0.49
MAPT P10636 2/20 0.49
MEN1 O00255 1/20 0.49
HTT P42858 1/20 0.49
GAA P10253 4/20 0.47
PKM P14618 3/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
TSHR P16473 1/20 0.47
CASP6 P55212 1/20 0.47
TP53 P04637 1/20 0.47
ALOX15 P16050 1/20 0.47
HSD17B10 Q99714 1/20 0.47
HPGD P15428 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL110723 0.98 SMN1; SMN2 (0.61) ATMSMN1; SMN2RAB9ANPC1LMNA
Methane SCHEMBL4160895 0.96 SMN1; SMN2 (0.59) ATMSMN1; SMN2RAB9ANPC1LMNA
SCHEMBL375177 0.96 SMN1; SMN2 (0.59) ATMSMN1; SMN2RAB9ANPC1LMNA
SCHEMBL14340531 0.76 KDM4E (0.65) ATMSMN1; SMN2RAB9ANPC1LMNA
SCHEMBL1171430 0.76 MEN1 (0.69) ATMSMN1; SMN2RAB9ANPC1LMNA
SCHEMBL14557079 0.75 CXCR4 (0.52) SMN1; SMN2LMNAKMT2AMAPTMEN1
SCHEMBL14112987 0.74 USP30 (0.47) ATMLMNAKDM4EALDH1A1KMT2A
SCHEMBL23731899 0.74 SMN1; SMN2 (0.42) ATMSMN1; SMN2RAB9ANPC1LMNA
SCHEMBL353890 0.74 SMN1; SMN2 (0.63) ATMSMN1; SMN2RAB9ANPC1LMNA
SCHEMBL10813449 0.74 SMN1; SMN2 (0.42) ATMSMN1; SMN2RAB9ANPC1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025013869-A1 FLUORINE-CONTAINING POLYMER HAVING NITROGEN-CONTAINING AROMATIC RING, PRODUCTION METHOD THEREFOR, AND COMPOSITION THEREOF ダイキン工業株式会社 2025-01-16 WO disclosed